Milk Thistle Extract
Latin Name: Silybum marianum (L.)
Active Ingredients: Silymarin, Silybin
Specifications: 20%-95%
Product Type: Light-yellow powder
Part of Plant Used: Seed
Extract Method: Ethanol and Water

Silybin
CAS No.: 22888-70-6
Molecular forula:C25H22O10
Molecular Weight:482.44

Main specification

silymarin 80%(UV) silybin+isoilybin 30%(HPLC)
silymarin 80%(UV) silybin 30%(HPLC)

The Introduction of milk thistle

Milk thistle has the efficacy for liver protecting, improving the function of liver, promotis biliation and diminishing liver inflammation. As a kind of better antioxidant, it can clea free radical in human body, postpone senility. Silymarin can protect the liver from damage of alcohol, chemical toxicant, drug, food poison, accelerate liver cell regenerating and repairing. So it is called "The natural liver-protection drug". In addition, Silymarin has the function of anti radiation and, arteriosclerosis preventing, skin-aging delaying. It is widely used in drug, health products, food and cosmetics.

What is Silymarin?

Silymarin is a unique flavonoid complex—containing silybin, silydianin, and silychrisin—that is derived from the milk thistle plant.Poor water solubility and bioavailability of silymarin led to the development of enhanced formulations. a new complex of silybin and natural phospholipids was developed. This improved product is known by the name of Silyphos. By complexing silybin with phospholipids, scientists were able to make silybin into a much more soluble and better-absorbed form. This silybin/phospholipid complex (Silyphos) was found to have significantly improved bioavailability, up to ten times better absorption, and greater effectiveness.

Main Functions:

1> Protect liver, improve liver function, promote the secretion of bile and inflammation
2> Strong antioxidant, can remove the body of free radicals, delay senescence
3> Prevent alcohol, chemical toxin, heavy metal, drugs, food toxins, the environment pollution and so on of the damage to the liver, and promote the regeneration of liver cells and repair

Pharmacological:

(1). Protective effect of liver;

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(2). Antioxidant;
(3). Hypolipidemic
· Provide heart benefits by lowering cholesterol levels
· Help diabetes in people who have type 2 diabetes and cirrhosis
· Reduce growth of cancer cells in breast, cervical, and prostate cancers
Clinical efficacy: Milk Thistle extract is mainly used for viral hepatitis, acute and chronic hepatitis, cirrhosis, fatty liver, nutrition, metabolic disorders and cardiovascular disease.

Application:

It is used in pharmaceutical, health product field with the form of suppository, lotion, injectio, tablets, capsules and other preparations.

Quality

ITEM	SPECIFICATION
Description:
Appearance	Light yellow or white powder
Odor	Characteristic
Particle size	100% pass through 80 mesh sieve
Tests:
Loss on drying(5h at105°C)	≤5.0%
Ash(3h at 600°C)	≤5.0%
Total Heavy Metals	≤10ppm
Plumbum	≤2ppm
Arsenic(as AS2O3)	≤2ppm
Residual Solvents	Eur. Pharm. 2000
Microbial:
Total bacterial count	Max.1000cfu/g
Yeast & Mould	Max.100cfu /g
Escherichia coli presence	Negative
Salmonella	Negative

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Hot extract

Standard extract

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milk thistle extract 80% silymarin

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